Glen Parker*
Department of Pharmacy, University of Toronto, Ontario, USA
Received: 01-Mar-2023, Manuscript No.JOMC-23-92939; Editor assigned: 03-Mar-2023, Pre QC No. JOMC-23-92939(PQ); Reviewed: 17-Mar-2023, QC No. JOMC-23-92939; Revised: 24-Mar-2023, Manuscript No. JOMC-23-92939(R); Published: 31-Mar-2023, DOI: 10.4172/J Med.Orgnichem.10.1.005
Citation: Parker G. Comprehensive Guide to Antipyretic Drugs: Understanding Their Common Uses. RRJ Med Orgnichem. 2023;10:005
Copyright: © 2023 Parker G. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Antipyretic drugs are medications that are used to reduce fever. They are also known as fever-reducing drugs or fever-reducing medications. Fever is a common symptom of many illnesses, and antipyretic drugs are often used to relieve the discomfort associated with fever. There are several types of antipyretic drugs, including acetaminophen, ibuprofen, and aspirin. Each of these drugs works in a slightly different way to reduce fever, but they all have the same basic goal: to lower the body's temperature and provide relief from the symptoms of fever [1].
Acetaminophen is a commonly used antipyretic drug. It is widely available without a prescription in many nations and is usually regarded as safe when used as recommended. Acetaminophen is often used to treat mild to moderate fever, as well as to relieve pain and inflammation. It is available over the counter in many countries, and is generally considered safe when used as directed.
Ibuprofen is another common antipyretic drug. It works by blocking the production of certain enzymes in the body that are responsible for causing inflammation. Ibuprofen is often used to treat moderate to severe fever, as well as to relieve pain and inflammation. Like acetaminophen, it is available over the counter in many countries and is generally considered safe when used as directed [2].
Aspirin is an antipyretic drug that has been used for many years. It works by blocking the production of certain chemicals in the body that are responsible for causing inflammation and fever. Aspirin is often used to treat moderate to severe fever, as well as to relieve pain and inflammation. However, aspirin is not recommended for use in children or teenagers due to the risk of a rare but serious condition called Reye's syndrome. Despite the fact that aspirin is a salicylate, it is technically a nonsteroidal anti-inflammatory medication. (NSAID). Salicylates, like NSAIDs, block tissue cyclooxygenases (Cox-1 and -2), which results in a reduction in the production of proinflammatory prostaglandins, strong mediators of pain and inflammation.
However, aspirin is a noncompetitive and irreversible inhibitor of Cox-1, which makes its effects more persistent and difficult to reverse than those of ordinary NSAIDs. For as long as a platelet is alive, aspirin exerts strong actions that suppress platelet activity. The reason for aspirin's frequent stomach side effects, link with peptic ulcer disease, and tendency to cause gastrointestinal bleeding is that it has strong and long-lasting effects on Cox-1 in gastric epithelial cells [3]. It is important to note that antipyretic drugs do not treat the underlying cause of fever. Instead, they provide relief from the symptoms of fever. In many cases, fever is a natural response of the body to infection or illness, and lowering the body's temperature can actually interfere with the body's natural healing process [4].
Few general side effects of antipyretic drugs
One of the most common side effects of antipyretic drugs is gastrointestinal issues. This includes nausea, vomiting, abdominal pain, and diarrhea. These symptoms can be mild or severe and can occur with both short-term and long-term use of antipyretic drugs. It is recommended that users take these drugs with food or milk to minimize the risk of stomach upset. Another potential side effect of antipyretic drugs is damage to the liver and kidneys. Long-term use of these drugs can cause damage to the liver and kidneys, especially when taken in high doses. This can lead to liver and kidney failure, which can be life-threatening. In rare cases, antipyretic drugs can cause an allergic reaction. This can include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat [5].
Finally, excessive or long-term use of antipyretic drugs can lead to rebound headaches. This occurs when the body becomes dependent on the drug and experiences withdrawal symptoms when the drug is stopped. This can lead to more frequent or severe headaches, which can be difficult to treat.
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