A Case with Uncommon Presentations Triggered by Bleeding and Rupture of Nodular Regenerative Hyperplasia in Cirrhosis after Taking Herbs
Background: Bleeding and spontaneous rupture of liver nodular mass in cirrhosis is an unprovisional episode, pushing patients into potential of fatal consequence. The definitive cause is still unclear. Objective: Aiming to raise physicians' awareness of adverse effects of herbs and Terlipressin, property of special type of bleeding under liver capsule as well. Methods: Retrospectively described a 53 year old man with unbearable abdominal distention after taking Chinese herbal medicine only 3 days. The rescue of case stirred some controversials about diagnostic and therapeutic aspects due to the unique presentations and the disease's dramatic changes. Results: Bleeding and rupture of nodular regenerative hyperplasia under liver capsule developed abrupt shock and ultimate fatal consequence. Secondary cerebral hemorrhage maybe the root cause of mortality. Conclusion: Some types of herbs, with property of promoting blood/qi circulation, may induce liver nodular mass bleeding and rupture secondary tissue necrosis. Bleeding from liver capsule and nodular carcinomarized transformation should be paid more attention to reduce medical errors.
Jia Z*, Zhou Y, Kong S and Ni J
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