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A Clinical Study on Rejuvenation of Periodontium With Enamel Matrix Protein (Emdogain) in Intra Bony Defects

Abstract

Aim: The present study was aimed at evaluating the use of enamel matrix derivative (Emdogain®) protein for periodontal regeneration in the treatment of deep intra bony osseous defects. Patients with systemic involvement, furcation involvement, one and two walled defect and defect involving the anterior teeth were excluded in this present study to find out the exact effectiveness of the material. Material & Methods: A total of ten patients (6 males and 4 female) in the age group between 20 to 30 years, who has osseous defects measuring Probing Pocket Depth (PPD) ≥ 8 mm; Clinical Attachment Level (CAL) ≥ 9 mm and intrabony defect depth ≥ 5 mm were included in the study. These patients were treated for adult periodontitis with Emdogain®. Prior to surgery the indices for oral hygiene and soft tissues assessment were also recorded. Statistical analysis: Paired t-test for individual samples was used for statistical analysis. If the probability value (P) was less than 0.05, it was considered significant. Results: After a one year study, surgical re-entry was made and the Data from this study demonstrated that application of (EMD) Emdogain gel resulted in a statistically significant, increase in root coverage, gain in the clinical attachment level (CAL), and probing pocket depth (PPD) reduction. Conclusion: The current findings confirm the previous reports and document that pocket closure and healthy periodontal conditions were obtained by this Emdogain therapy.

Dr. Jayachandran Dorairaj, Dr. Rohit Radhakrishnan, Dr. Sunantha Selvaraj, Dr. Ravi Saranyan, Dr. Priya

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