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Comparative Studies of Brands of Paracetamol
Tablets in Misurata Market, Libya
Abstract
Post marketing in-vitro studying of products is an important to
investigate quality of medicines at various intervals time during their
shelf life. Paracetamol is a widely used analgesic and antipyretic drug
worldwide. The selected five brands of Paracetamol tablets in Misurata
market, Libya, were tested for various parameters of quality control
tests. 120 tablets for each brand were required to achieve: Uniformity
of drug content, weight variation, hardness, friability, disintegration
time and dissolution. All brands showed acceptable friability values less
than 1% except Aspar® Paracetamol tablets were represent extremely
high value around twenty times more than standard level. Omar Rwaiha
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