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Differentiation of mesenchymal stem cells into Osteoclasts for potential bone regeneration using Vitamin B3

Abstract

The bone cells (osteocytes and osteoclasts) do not replicate and thus the maintenance of a healthy bone must rely on an exogenous source of cells. Currently, bone fracture management is effectively done by surgeons and the healing process post-operation relies mostly on self-recovery. In view of the aforementioned inadequacies regarding bone regeneration, we opted to test the efficacy of Vitamin D3 known to induce bone formation postoperation. Methods: Rat

Mr RO Ogunshina

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