Research Article Open Access

Early Evaluation of Etilological Treatmetn in Young Adults, Chronically Infected Trypanosama Cruzi Detected Using Polymerase Chain Reaction

Abstract

Fourteen patients (age limits: 18-30) chronically infected with Trypanosoma cruzi and presenting positive blood PCR reactions, were submitted to etiological treatment with benznidazole, in Nagapattinam district rural an area. A control group of five patients of the same age and positive by PCR did not receive treatment. Post-treatment follow-up was performed with PCR and conventional serology. PCR became negative in 12/14 of the treated patients after six months follow up, compared to 1/5 in the control group (p = 0.01). All patients remained serologically positive after treatment. The reduction of PCR signals of infection after treatment may become an early evidence of cure in chronically infected young adult patients.

K.Sathish, Dr.S.Niraimathi, S.Justin Jayaraj, K.Kamalakannan

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