Research Article Open Access

Efficacy of Ethanolic Extracts for Two Plants on Wound Healing in Diabetic Albino Rats

Abstract

Background: Wounds in diabetic patients are critical to treat. The use of allopathic drugs has various side effects. New natural sources for therapies are so required.

Materials and methods: This research aim to determine the possibility for wound healing for the ethanolic extract of Eucalyptusglobulus leaves and Curcuma longa rhizomes. To find out how plant extracts affected diabetic rats' wound healing, albino rats were given oral administration of various plant extracts.

Results: These plant extracts greatly accelerated the wound's ability to close in rats associated with diabetes or non-diabetes (P<0.05) this increases the proliferation and migration of the fibroblast result with a faster healing process. These plant extracts do not cause cytotoxicity. After treatment with extracts the proliferative assay that showed the least amount of cell death. Results found positive.

Conclusion: This research may indicate that the combination of ethanolic extracts of both plants have potential as novel therapies for diabetic patients wound healing.

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