Mini Review Open Access

Evaluation of Albumin Administration in Canine Patients: Necessity, Risks and Current Perspectives

Abstract

Albumin plays a major role in maintaining physiological functions in dogs, serving as a carrier protein and contributing to colloid osmotic pressure regulation. In veterinary medicine, albumin administration is essential for managing hypoalbuminemia in critically ill dogs. While Canine Serum Albumin (CSA) is the preferred choice to moderate hypersensitivity risks, constraints in availability and cost often lead to the use of heterologous albumins like human serum albumin and bovine serum albumin. However, the use of heterologous albumins poses significant challenges, including the potential for fatal hypersensitivity reactions. This review focus on the necessity and application of albumin in dogs, critical issues associated with heterologous albumin administration and the current status of CSA use. Future strategies should focus on enhancing the availability of CSA and exploring safer alternatives to ensure effective albumin therapy in canine patients.

Hyun-Jung Han*

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