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Evaluation of invitro antihelmintic activity of whole plant extracts of tridax procumbens Linn

Abstract

The aqueous, methanol and chloroform extracts of Tridax procumbens Linn belonging to the family Asteraceae were evaluated for anthelmintic activity. The dried powder of whole plant of Tridax procumbens was extracted and the anthelmintic activity was studied. Aqueous, methanol and chloroform extracts collected were tested for anthelmintic activity against Indian adult earthworm Eisenia fetida and recorded the time taken for induction of paralysis and death. Two concentrations (50 mg/ml and 100 mg/ml) of aqueous, methanol and chloroform extract were evaluated in the bioassay involving determination of time of paralysis (P) and time of death (D) of the worms. Albendazole (100 mg/ml) was used as reference standard and normal saline solution as a control. Comparative results of present study indicated that the aqueous, methanol and chloroform whole plant extracts of Tridax procumbens Linn shows significantly dose depending pharmacological activity on the Indian earthworms.

Vaishnavi Sanjiv Patil*, Chaitali Milind Diwane

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