Research Article Open Access

Impact of Pharmacist Intervention in the Management of Intravenous to Subcutaneous Insulin Transition: A Quasi-Experimental Pre-Post Study

Abstract

Objective: To determine the percentage of blood glucose within a goal range of 110-180 mg/dL during the 48-hour period following intravenous to subcutaneous insulin transition with and without pharmacist intervention. Methods: This quasi-experimental pre-post study was a retrospective pre-intervention cohort involving adult non-intensive care unit (ICU) patients was compared to a retrospective post-intervention cohort during intravenous to subcutaneous insulin transition. The primary outcome was the percentage of blood glucose within a goal range of 110-180 mg/dL during the 48-hour period following intravenous to subcutaneous insulin transition. Results: The pre-intervention group involved 32 patients and 397 BG values, and the post-intervention group involved 34 patients and 400 BG values. The percentage of BG values within the goal range of 110-180 mg/dL was higher in the post-intervention group compared to the pre-intervention group (35.3% vs 18.1%, p<0.001). Conclusion: Incorporating pharmacist intervention during the intravenous to subcutaneous insulin transition process significantly increased the percentage of BG values within goal range (110-180 mg/dL) and decreased the percentage of BG ≥300 mg/dL during the 48-hour period following the transition.

Juri Na*, Jill Zaccardelli, Brian Morini, Julie Willmon, Ramy Girgis

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