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In-vitro Sensitivity of Otomycotic Agents against Syenthetic Antifungals and Natural Herbs

Abstract

In vitro sensitivity methods against various antifungals were performed for otomycotic agents isolated from 10 patients. The agents were isolated on SDA supplemented with chloramphenicol @ 30μg/100ml. The common fungi isolated were Aspergillus fumigatus, A. flavus, A. terreus, A.alternata, Paecilomyces, and Candida albicans. These clinical isolates were subjected to in vitro sensitivity methods against synthetic antifungals and natural herbs and spices. The in vitro sensitivity methods applied were disc diffusion method, E test and broth dilution method. The most effective antifungal was itraconazole and garlic was the most effective amongst the natural products tested.

Sapna Rai, Sanchali Padhye and Nidhi Narula

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