Review Article Open Access

Is Chemo-Metrics Showing the Pathway for Unsolved Questions in Chemical / Drug Analysis?.

Abstract

Analytical chemistry is the science of modeling quantitative measurements. Basically, it is the quantification of analytes in combined dosage forms samples which exhibits as the crucial part of the subject. Mainly, it is the radical apprehension of practical aspects of analysis, and the ability to identify a problem which cannot be solved by the existing analytical methods/techniques that motivate an analyst to develop creative approaches or new analytical methods. The answer to the all problems faced in analysis is chemometrics. Chemometrics has been defined as elementary tool for the implementation of mathematical and statistical methods to chemical measurements. Chemometric methods are often applied in situations when no sufficient theory is available for describing or solving analysis problems. The aim of chemometrics is to find out hidden relationships exist between the available data and the desired information. The prominent problems in chemistry are: recognition of the chemical structure from spectral data (spectral elucidation), quantitative analysis of chemical substances in complex mixtures (multivariate calibration), and determination of the origin of samples (cluster analysis and classification), and prediction of properties or activities of chemical compounds or technological materials (quantitative structure-activity or structure-property relationships). This literary work includes the basics of chemometrics and its aid to put this novel analytical discipline into application to face the present challenges of analytical chemistry.

Ritika, Navdeep K Gill, Ravindra K Rawal, and GS Sarma

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