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Medication Adherence Pattern, Associated Factors and outcomes among Hospitalized Heart Failure Patients in a Tertiary Hospital in Tanzania: A Prospective Cohort Study

Abstract

Managing heart disease is complex and multifaceted, but adherence to medication remains the cornerstone of avoiding avoidable readmissions, premature deaths, as well as needless costs in health care. Despite the evidence-based effectiveness of anti-fraud drugs, poor adherence is widespread and also remains a significant barrier to improving clinical outcomes in cardiac insufficiency populations. We enrolled 459 patients with established diagnosis of heart failure. Sociodemographic, clinical, laboratory, and echocardiographic data were gathered using a structured questionnaire during the hospital admission of enrollment. The Medication adherence is being assessed using the 8-item Morisky Medication Adherence Scale (MMAS-8). The primary outcome measures were rehospitalization and mortality at 180-days. Linear logistic regression analyses were used to assess for factors associated with adherence and predictors of rehospitalization. Based on their’s adherence status, the participants were compared with respect to survival using Cox proportional-hazards regression model. All tests were 2-sided and p<0.05 was used to denote statistical significance.

Pedro Pallangyo

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