Mini Review Open Access

Multi-Unit Particulate Systems for Rapid Formulation Development of New Chemical Entities

Abstract

Drug product development of New Chemical Entities (NCE) is a critical aspect of bringing a new drug molecule to market. Time is of essence in NCE development programs and emphasis is placed on speed, in terms of product development and commercialization. For many NCE programs, the cost of Active Pharmaceutical Ingredient (API) and availability are a bottleneck and therefore creative ways are needed to make use of the limited API to advance drug product development. Multi unit particulate systems offer one such advantage in leveraging limited API for pharmaceutical developmental intended for clinical use. Current technologies, such as oral Multiparticulate Drug Delivery Systems (MDDS), have gained immensely in importance, not only because of their ability to control drug release, but also for the modified drug-release profiles they facilitate.

Abdul Khader Mohammad

To read the full article Download Full Article | Visit Full Article