Review Article Open Access

Novel Delivery Systems in Cancer Chemotherapy

Abstract

The development of drug delivery systems for cancer therapeutics has improved the therapeutic efficacy of existing chemotherapies and also resulted in the creation of new ones. A variety of these technologies are already in clinical use, including controlled delivery systems for cancer drugs, localized chemotherapy systems, polymer-drug conjugates, liposomal systems, and trans dermal drug delivery patches. The possibility of targeting the delivery of cancer drugs to tumor tissues may be realized by using specific polymer-drug conjugates or by manipulating the physicochemical properties of polymers or liposomal systems to match the tumor environment. A controlled release microchip has been developed that can dispense one or more drugs as needed and represents the next generation of ―smart‖ drug delivery approaches. Drug-delivery systems have had a growing influence on the clinical application of cancer therapeutics for several decades, and novel delivery systems now have been used by millions of patients.

N Rathna Prasanna, C Triveni, R Soumya, BV Ramana and G Nagarajan

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