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Novel Synthesis, And Biological Evaluation of Four Co-Ordinate Co (Ii)-Complexes Derived From 5-Amino 2(4’thiazolyl)1 hbezimidazole (ATBZ) And Heterocyclic Bases

Abstract

Four coordinate Co (II) adducts were synthesized by the reaction of CoCl2.6H2O with and 5- aminothiabendazole as chelate ligand in ethanol and heterocyclic bases in the ratio 1:1:1. The synthesized compound ATBZ was elucidated by elemental analysis, 13C, 1H NMR. The synthesized adducts were characterized by elemental analysis, magnetic measurements, conductivity measurements. Screenings of antimicrobial activity of prepared metal complexes were also carried out against different bacterial species such as Pseudomonas putida, Escherichia coli, and fungal species such as Aspergillus Nigar, Candida Albicans, Yields of the synthesized compounds were found moderate and some of them also indicated potent activity against bacterial and fungal species.

Dr.J.R.Gujarathi, Assi Prof.T.V. Rajale

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