Review Article Open Access

Phytochemical, Pharmacological and Pharmacognostical Profile of Vernonia anthelmintica: An Overview

Abstract

The aim of this review is to analyze published data on the pharmacological, Phytochemical and Pharmacognostic profile of plant Vernonia anthelmintica Willd genus. This will help to identify the state of knowledge in regard to this plant species and to propose future research priorities. Material and Method-The major scientific databases including Science direct, cab direct, CeRA, Proquest and Google Scholar were queried for information on Vernonia anthelmintic using various keyword combinations. The International Plant Name Index was also used to verify the names of the plant. Result-The Vernonia genus has about one thousand species and members of the genus are widely used as food and medicine. A total of 109 Vernonia species were reported in the literature to have medicinal properties. Vernonia anthelmintica Willd belongs to the family Compositae and has been used for curing asthma, hiccough, inflammatory swellings, sores, and itching of the eyes. Conclusion-On the basis of results from a combination of pharmacological, phytochemical and pharmacognostic studies reported, Vernonia anthelmintica holds the most promise for development into against diabetes and potential against cancer and inflammatory conditions. Vernodalidimers A and B is so far the most promising agent from the plant that has potential for development into an anti-cancer agent. Vernoanthelcin A–I effects on estrogen biosynthesis in human ovarian granulosa-like cells. The Vernonia anthelmintica and isolated compounds require further studies to ascertain its medicinal potentials.

Rajani Srivastava, Amita Verma, Alok Mukerjee, and Neetu Soni

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