Review Article Open Access

Psoriasis Research: A Comprehensive Review

Abstract

Psoriasis is basically an inflammatory skin disorder with receptive irregular epidermal differentiation and hyperproliferat ion influencing 2-3 % of world’s population. Pathophysiology of the psoriasis incorporates mostly the enactment and migrate ion of T-cells to the dermis activating the release of cytokines which causes the inflammation and the triggered generation of skin cells. The likely factors and prompts causing psoriasis incorporate passionate anxiety, skin damage, systemic diseases, intestinal upsets and certain medications. There are different types of psoriasis such as plaque psoriasis, psoriatic joint pain, scalp psoriasis, guttate psoriasis, flexural psoriasis, nail psoriasis, pustular psoriasis, erythrodermic psoriasis which can be analyzed by clinical diagnosis, for example, skin biopsies etc. Therapeutic drugs that either regulate the immune system or normalize the differentiation program of psoriatic keratinocytes are proposed for treatment of psoriasis. Based on the kind of psoriasis, its area of origin, degree and seriousness there are different treatment regimens accessible for psoriasis, for example, topical drugs, systemic operators, phototherapy and homeopathic approach which can control the symptoms.

Jagmeet Singh, Poonam Jaggi and Shivangi Shukla

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