Review Article Open Access

Role of Amlodipine and Hydralazine in the Management of Chronic Mitral Valve Degeneration

Abstract

This comprehensive review explores the potential of amlodipine and hydralazine as major treatments for chronic mitral valve degeneration in dogs. Focusing on their mechanisms as arterial dilators, the paper evaluates the effectiveness of these agents in the context of both human and veterinary medicine. While hydralazine has seen varying degrees of success and acceptance in human patients due to its mixed results in long-term treatments, amlodipine has shown promising outcomes without significant side effects. The review highlights the need for further species-specific studies to better understand the applicability and effectiveness of these drugs for canine chronic mitral valve degeneration, proposing a potential shift in the pharmacological management strategies for canine mitral regurgitation.

Seunggon Lee*

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