Research Article Open Access

Techniques of Tablet Coating: Concepts and Advancements: A Comprehensive Review

Abstract

Tablet coating is one of the oldest pharmaceutical processes still is existence. Coating is a process by which an essentially dry, outer layer of coating material is applied to the surface of a dosage form in order to confer specific benefits over uncoated variety. It involves application of a sugar or polymeric coat on the tablet. The advantages of tablet coating are taste masking, odor masking, physical and chemical protection, protects the drug in the stomach, and to control its release profile. Coating may be applied to a wide range of oral solid dosage form, such as particles, powders, granules, crystals, pellets and tablets. When coating composition is applied to a batch of tablets in a coating pan, the tablet surfaces become covered with a tacky polymeric film. There are several techniques for tablet coating such as sugar coating, film coating and enteric coating. The disadvantages of the older techniques of coating have been overcome with the recent advancement in coating technologies. In these technologies coating materials are directly applied on the surface of the tablet without the use of any solvent. ICH guidelines also prefer the avoidance of organic solvents in pharmaceutical dosage formulations considering products safety profile. This review discusses the basic concepts of tablet coating, the recent advancements made, the problem faced during the process, their solutions and coating evaluation.

Aalok Basu , Anjan De and Suddhasattya Dey

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