e-ISSN: 2319-9849
Halimat Adedeji
University of KwaZulu- Natal, South Africa
ScientificTracks Abstracts: Research & Reviews: Journal of Chemistry
What is the status of reporting adverse drug reactions directly by healthcare consumers in Africa? Direct reporting by health care consumers has been adopted in some developed and developing countries with a positive impact in improving pharmacovigilance through increased reporting rate. There are limited reports on direct reporting and its outcome in Africa. To identify and present the available evidence on direct reporting of adverse drug reactions by healthcare consumers in Africa. A review guided by Cochrane handbook was conducted. Electronic scientific databases such as PubMed, Cumulative Index to Nursing and Allied Health Literature, Embase and Cochrane Library were searched. Google scholar, general Google search engine, the website for the regulatory resources for Africa and World Health Organisation - Uppsala Monitoring were also searched for available guidelines, documents and publications. The review period was January 1992 to October 2019. Results: This study identified 16 African countries that have included healthcare consumers as eligible to report in their policy/ guidelines. There is low awareness on pharmacovigilance. Eight (8) African countries have formally launched direct reporting which are 14.2% of African countries. There is a wide range of difference between the rate of report submitted by health care consumers as compared with healthcare workers. Paper form, text messages, telephone and web application-based reporting system have been used by different countries that have launched direct reporting. Poor infrastructure, low awareness and lack of a reporting culture are major challenges while the availability of common reporting methods is a potential opportunity of promoting direct reporting. Few African countries have adopted and launched direct reporting. Published legal framework, policies, guidelines and studies on direct reporting are limited. Availability of a system and reporting method are opportunities to improve and overcome probable challenges. Keywords: Advanced Chemistry, Organic reactions , Medicinal chemistry
A principal pharmacist PhD student under supervision of Prof. Manimbulu Nlooto at University of KwaZulu- Natal, South Africa.