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conferenceseries
.com
Volume 5, Issue 6 (Suppl)
J Mat. Sci.
ISSN: 2321-6212
Advanced Materials 2017
October 26-28, 2017
OCTOBER 26-28, 2017 OSAKA, JAPAN
13
TH
INTERNATIONAL CONFERENCE ON
Advanced Materials and Nanotechnology
Alginate/κ-Carrageenan and alginate/gelatin composite hydrogel beads for controlled drug release of
curcumin
Jinu George
Sacred Heart College Thevara, India
H
ydrogel beads based on natural polymers like alginate, κ-Carrageenan and gelatin represent an efficient scaffold for
controlled hydrophobic drug delivery. We report herein the development and characterization different formulations
of hydrogel systems based on the above mentioned polymers having adequate properties as drug delivery matrices. Different
combinations of alginate/κ-Carrageenan and alginate/gelatin hydrogel beads were developed and drug release properties
were compared using curcumin as a model drug. Alginate/κ-Carrageenan hydrogel beads with 50:50 weight ratio exhibited
higher swelling and better drug release percentage than compared to other beads. Antibacterial activity of curcumin released
from hydrogel beads against
B. cereus
was established by disc assay. Encapsulation efficiency and drug release behavior of
different formulations of alginate/κ-Carrageenan and alginate/gelatin, indicates that the polymer blends synthesized possess
considerable potential in pharmaceutical and medicinal applications.
jinujacobv@gmail.comJ Mat. Sci. 2017, 5:6
DOI: 10.4172/2321-6212-C1-009