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conferenceseries
.com
Volume 6
Research & Reviews: Journal of Material Sciences
Advanced Materials 2018
September 19-21, 2018
September 19-21, 2018 Tokyo, Japan
22
nd
International Conference on
Advanced Materials and Nanotechnology
Res. Rev. J Mat. Sci. 2018, Volume 6
DOI: 10.4172/2321-6212-C4-024
Protein-templated biomimetic synthesis of luminescent noble metal nanocluster for biomedical
applications
Meegle S Mathew and Kuruvilla Joseph
Indian Institute of Space Science and Technology, India
R
ecently, protein-directed biomimetic mineralization has been demonstrated to be an efficient and promising strategy for
synthesis of metal nanocluster for biomedical applications. This method is found to be bio-inspired, straightforward and
environmentally benign. It can produce intense emitting fluorescent nanocluster with good stability, excellent biocompatibility,
high water solubility and rich surface functional groups for further bio-conjunction. Fluorescent noble metal quantum
clusters are composed of several tens of atoms and are distinctly different from bulk and metallic nanoparticles. They have
sub-nanometer core size with discreet energy levels and show molecule like optical properties. Their easy one step and green
synthesis make them particularly attractive. We have prepared protein directed synthesis of gold, silver, copper and gold-
silver alloy quantum clusters. The formed highly stable quantum clusters showed intense fluorescence emission and were
characterized using UV-Vis spectroscopy, fluorescence, FTIR spectroscopy, Transmission Electron Microscopy (TEM) and
X-ray Photoelectron Spectroscopy (XPS). These quantum clusters further can be used for biomedical application including
biosensing, such as sensing of biomolecules including neurotransmitter-acetylcholine, creatinine, bilirubin and detection of a
toxic metal ion, mercury and the utilization of metal nanocluster for contraceptive applications.
meeglesmathew@gmail.com