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Volume 5, Issue 5 Res. Rev. J Mat. Sci. 2017
ISSN: 2321-6212 Advanced Materials 2017
September 07-08, 2017
September 07-08, 2017 | Edinburgh, Scotland
Advanced materials & Processing
11th International Conference on
Natural plant-derived polymer fabricated with sugar-containing hydroxyapatite for biocompatible bone-
hemostasis
Yeonjeong Noh1, T. Umeda1, T. Musha2, T. Sasaki 3 and K. Itatani1
1Sophia University, Japan
2Toho University, Japan
3Shizuoka University, Japan
The preparation conditions of bone-hemostasis materials were examined using hydroxyapatite (Ca10(PO4)6(OH)2: HAp) and
natural plant-derived polymer(guar gum(GG), locust bean gum(LBG) and sodium alginate(AG)). The starting gel was prepared
by dissolving 2 mass% 80LBG-20GG and 2 mass% AG into deionized water heated at 60ºC (80LBG-20GG/AG). The resulting gels
were vigorously agitated with 20,000 rpm for 3 min. Further, the gel was immersed into 3 mass% phosporyl oligosaccharides of
calcium (POs-Ca®50) solution at room temperature for 24 h. Then, the resulting gel was hydrothermally-treated 100ºC for 5 h and
freeze-dried at -50ºC for 24 h to form s-HAp in the material. According to the X-ray diffractometry (XRD), Fourier transform
infrared spectrometry (FT-IR) and confirmed by the terahertz spectroscopy, the resulting composite contained hydrolyzed materials
of POs-Ca, i.e., the sugar-containing HAp (s-HAp), as well as LBG and GG. According to the micro-computed tomography (micro-
CT) and differential thermal analysis and thermogravimetry (DTA-TG), 16.8% of HAp could be homogeneously dispersed within
the porous composite material. The pore sizes were approximately 1 to 2 µm determined by scanning electron microscopy (SEM).
The present 80LBG-20GG/AG/s-HAp composite showed the noted porosity (81%; the measurement by micro-CT), absorption of
simulated body fluid (1426%), adhesive strength (28.1 N) and hemostat time (7.5 h; the measurement by using simulated blood).
The composite is also expected to assist the osteogenesis with its s-HAp. Overall, the composite of s-HAp and natural plant-derived
polymer seems to be a promising material for the bone hemostasis and regeneration.
Biography
Yeonjeong Noh is a student of Sophia graduate school. Her research interest is the fabrication of bone hemostasis and bone regenerate properties with natural
plant-derived polymer fabricated with hydroxyapatite.
Yeonjeong Noh et al., Res. Rev. J Mat. Sci. 2017, 5:5
DOI: 10.4172/2321-6212-C1-006