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Research & Reviews: Journal of Material Sciences | ISSN: 2321-6212 | Volume 6
Theoretical, Materials and Condensed Matter Physics
5
th
International Conference on
November 26-28, 2018 | Los Angeles, USA
The rate of entropy model for irreversible reactions in living systems
Roberto Zivieri
University of Messina, Italy
A
n analytical model to compute the rate of entropy in living systems is developed basing on the equations of heat and mass
diffusion. The model is applied to the most interesting case of the metabolic network, the glucose catabolism in normal and
cancer cells. This is done treating the cell as an open thermodynamic system. It is shown that the rate of internal entropy is mainly due
to irreversible chemical reactions and that the rate of external entropy is mostly correlated to the heat flow towards the intercellular
environment. It is found that the ratio between the rates of entropy associated with respiration and fermentation processes has a space
and time dependence for diffusion of chemical species and is invariant for heat and irreversible reactions. Analytical and numerical
results show that in a cell Prigogine’s minimum dissipation principle is fulfilled in agreement with the local formulation of the second
principle of thermodynamics. The applications of these results could be important for cancer detection and therapy.
roberto.zivieri@unife.itRes. Rev. J Mat. Sci. 2018, Volume 6
DOI: 10.4172/2321-6212-C10-042