advanced-materials-2017-keynote

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Volume 5, Issue 5 Res. Rev. J Mat. Sci. 2017
ISSN: 2321-6212 Advanced Materials 2017
September 07-08, 2017
Page 72
Notes:
conferenceseries.com
September 07-08, 2017 | Edinburgh, Scotland
Advanced materials & Processing
11th International Conference on
Nekane Guarrotxena, Res. Rev. J Mat. Sci. 2017, 5:5
DOI: 10.4172/2321-6212-C1-004
SERS tag-therapeutic drug delivery, multimodal imaging, multiplexed sensing and diagnosis metal-
nanosystems
The high demand of multifunctional tools for effective labeling, imaging, sensing leading to both diagnostics and therapies,
in nanomedicine, could be addressed by using multifunctional nanomaterials. Noble metal nanoparticles (NPs) are
especially useful in this context. They exhibit optical excitations known as surface plasmons, extremely dependent on the NPs-
morphology, -assembly, and medium which establish the basis for the molecular recognition, imaging and sensing sensitivity.
On the other hand, these surface plasmons also induce large electromagnetic field enhancements, greatly useful in Surface-
enhanced Raman spectroscopy (SERS) technique. In fact, the exceptionally strong field enhancement at the interstitial sites
between coupled metal NPs, allows detection at the single molecule level; and due to the fingerprint capabilities of SERS, also
with high selectivity. Moreover, the relevant implementation of SERS tags design has opened new pathways and strategies
for the SERS application in the clinical and medical field. The plasmon resonance can either radiate light, which is a useful
applicability-process in optical and imaging fields, or be rapidly converted to heat with potential application in therapy and
drug loading field. In this contribution, I will present our own and up-to-date literature results regarding the promising use
of noble metal nanoparticles (NPs) for biomedical applications. In particular, I will describe NPs synthesis, assembly and
conjugation with biological and biocompatible ligands, plasmon-based labeling and imaging, sensing, diagnostic and therapy.
Biography
Dr. Nekane Guarrotxena earned her PhD in chemistry from the University of Complutense, Madrid-Spain in 1994. She held post-doctoral research positions at the Ecole
Nationale Superieure d´Arts et Metiers, Paris-France (1994-1995) and the University of Science II, Montpellier-France (1995-1997). She was the Vice-Director of the
Institute of Polymer Science and Technology (ICTP)-CSIC (2001-2005). From 2008-2011, she was visiting professor in the Department of Chemistry, Biochemistry and
Materials at University of California, Santa Barbara-USA and the CaSTL at University of California, Irvine-USA. She is currently Research Scientist at the Institute of Poly-
mers Science and Technology, CSIC-Spain. She has been involved for several years on the dissemination of Science and Technology of Polymers-plastics (where she
served as a member of Scientific Committee of Escuela de Plasticos y Caucho and FOCITEC orAssociation for the Promotion of Science and Technology). She is Editorial
Board member of some materials science and chemistry journals and Organizing Committee member of several scientific and technological events. She also serves as
Externalexpertise Consultant on I+D+I Management and Policy for National and International Agencies. Her studies have been published in more than 60 peer-reviewed
publications, 4 books (also co-editor) and 22 book chapters. Her research interest focuses on the synthesis and assembly of hybrid nanomaterials, nanoplasmonics, and
their uses in nanobiotechnology applications (bioimaging, drug delivery, therapy and biosensing).
Nekane Guarrotxena
Spanish National Research Council (CSIC), Spain