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Euro Pharma Chemistry & Future Pharma 2019
Volume 08
Research & Reviews: Journal ofPharmaceutical Analysis | ISSN : 2320-0812
June 27-28, 2019 | Amsterdam, Netherlands
12th World congress on
Joint Event
4
th
Pharmaceutical Chemistry Conference Future Pharma
Multidrug-resistant tuberculosis patients presenting with bronchiectasis and usefulness of
the six-minute walk test: A case series report with literature review
Patrick Lungu
University of Zambia, Zambia
M
ultidrug resistant tuberculosis (MDR-TB) is associated with extensive lung damage which impinges
on the quality of life during and post-treatment. The six-minute walk test (6-MWT) demonstrates
signi cance in predicting the cardiopulmonary functional status in tuberculosis patients with bronchiectasis.
We present a case series of MDR-TB patients with the multifarious manifestation of bronchiectasis and
response to the 6-MWT. We found bronchiectasis can occur in primary MDR-TB, which is attributed to
overwhelming in ammatory response and delay in diagnosis. Mycetoma was a common complication. The
6-MWTwas found to be useful as a bedside tool for predicting functional status. MDR-TB should be promptly
diagnosed to prevent life-limiting sequelae. The ndings in this case series challenge the assumption that
MDR-TB is less virulent and calls for more studies to understand its pathogenesis
Pharmaceutical Analysis 2019, Volume 08